MSD Manual

Please confirm that you are a health care professional

honeypot link

Liver Cytology in Small Animals

By

Sharon A. Center

, BS, DVM, DACVIM, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University

Last full review/revision May 2015 | Content last modified May 2015

Ultrasonographic-guided fine-needle aspirates are routinely used to confirm a diagnosis of HL in cats and to identify suppurative septic inflammation, neoplasia, and glycogen-like VH. However, definitive diagnosis of hepatic disease is otherwise impossible with liver aspirates because the absence of acinar architecture compromises anatomic orientation and correct interpretation. Cytologic interpretation of liver aspirates are notoriously discordant with histologic findings on biopsy specimens. Neither neoplasia nor sepsis can be definitively excluded using cytology, and inflammatory disease is too often suspected. Cytology should not be the basis to recommend immunomodulatory or antifibrotic medications or longterm chelation therapy for copper-associated hepatopathy. Rather, liver biopsy remains the standard for diagnoses of most hepatic disorders.

OTHER TOPICS IN THIS CHAPTER

Hepatic Disease in Small Animals
Overview of Hepatic Disease in Small Animals
Hematology in Hepatic Disease in Small Animals
Coagulation Tests in Hepatic Disease in Small Animals
Enzyme Activity in Hepatic Disease in Small Animals
Other Serum Biochemical Measures in Hepatic Disease in Small Animals
Hepatic Function Tests in Small Animals
Imaging in Hepatic Disease in Small Animals
Cholecystocentesis in Hepatic Disease in Small Animals
Liver Cytology in Small Animals
Liver Biopsy in Small Animals
Pathologic Changes in Bile in Small Animals
Nutrition in Hepatic Disease in Small Animals
Fulminant Hepatic Failure in Small Animals
Hepatic Encephalopathy in Small Animals
Portal Hypertension and Ascites in Small Animals
Portosystemic Vascular Malformations in Small Animals
Acquired Portosystemic Shunts in Small Animals
Other Hepatic Vascular Disorders in Small Animals
Hepatotoxins in Small Animals
Infectious Diseases of the Liver in Small Animals
Feline Hepatic Lipidosis
Biliary Cirrhosis in Small Animals
Canine Cholangiohepatitis
Canine Chronic Hepatitis
Lobular Dissecting Hepatitis in Small Animals
Canine Vacuolar Hepatopathy
Metabolic Diseases Affecting the Liver in Small Animals
Hepatocutaneous Syndrome in Small Animals
Nodular Hyperplasia in Small Animals
Hepatic Neoplasia in Small Animals
Miscellaneous Liver Diseases in Small Animals
Diseases of the Gallbladder and Extrahepatic Biliary System in Small Animals
Cholecystitis in Small Animals
Canine Gallbladder Mucocele
Other Disorders of the Gallbladder in Small Animals
Other Disorders of the Bile Ducts in Small Animals
Extrahepatic Bile Duct Obstruction in Small Animals
Cholelithiasis in Small Animals
Biliary Tree Rupture and Bile Peritonitis in Small Animals
Feline Cholangitis/Cholangiohepatitis Syndrome
Hepatobiliary Fluke Infection in Small Animals
Others also read
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID

Test your knowledge

Dental Development
Ruminants (cattle, sheep, and goats) lack which of the following teeth?
Become a Pro at using our website 

Also of Interest

Become a Pro at using our website 
TOP