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Other Disorders of the Gallbladder in Small Animals

By

Sharon A. Center

, BS, DVM, DACVIM, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University

Last full review/revision May 2015 | Content last modified May 2015

Gallbladder agenesis describes the congenital absence of the gallbladder. In the absence of congenital malformations of the intrahepatic biliary structures, this is an inconsequential abnormality.

Biliary atresia describes the congenital maldevelopment of intrahepatic biliary structures and is uncommonly encountered. Affected individuals are jaundiced and unthrifty at a young age. Prognosis is poor.

A bilobed gallbladder is occasionally identified in cats during ultrasonography or at surgery as an inconsequential abnormality.

Cystic mucosal hyperplasia of the gallbladder is also known as cystic mucinous hypertrophy, cystic mucinous hyperplasia, and mucinous cholecystitis (although it is not an inflammatory lesion). The role of steroid hormones in lesion induction remains unclear but is suspected. There is no associated inflammation, and the serosal surface of the gallbladder remains intact. These hyperplastic lesions are routinely identified in dogs with gallbladder mucocele, in which "cystic" structures are filled with tenacious viscoelastic mucin.

Gallbladder dysmotility is proposed as an emerging syndrome in dogs and may precede GBM development. The syndrome may be linked to steroid hormones, based on early observations of an apparent link between mucocele development and treatment with progestational compounds. Sex hormones (progestins, androgens) have been shown experimentally (in vitro) to reduce contractility of gallbladder smooth muscle in experimental animal models.

OTHER TOPICS IN THIS CHAPTER

Hepatic Disease in Small Animals
Overview of Hepatic Disease in Small Animals
Hematology in Hepatic Disease in Small Animals
Coagulation Tests in Hepatic Disease in Small Animals
Enzyme Activity in Hepatic Disease in Small Animals
Other Serum Biochemical Measures in Hepatic Disease in Small Animals
Hepatic Function Tests in Small Animals
Imaging in Hepatic Disease in Small Animals
Cholecystocentesis in Hepatic Disease in Small Animals
Liver Cytology in Small Animals
Liver Biopsy in Small Animals
Pathologic Changes in Bile in Small Animals
Nutrition in Hepatic Disease in Small Animals
Fulminant Hepatic Failure in Small Animals
Hepatic Encephalopathy in Small Animals
Portal Hypertension and Ascites in Small Animals
Portosystemic Vascular Malformations in Small Animals
Acquired Portosystemic Shunts in Small Animals
Other Hepatic Vascular Disorders in Small Animals
Hepatotoxins in Small Animals
Infectious Diseases of the Liver in Small Animals
Feline Hepatic Lipidosis
Biliary Cirrhosis in Small Animals
Canine Cholangiohepatitis
Canine Chronic Hepatitis
Lobular Dissecting Hepatitis in Small Animals
Canine Vacuolar Hepatopathy
Metabolic Diseases Affecting the Liver in Small Animals
Hepatocutaneous Syndrome in Small Animals
Nodular Hyperplasia in Small Animals
Hepatic Neoplasia in Small Animals
Miscellaneous Liver Diseases in Small Animals
Diseases of the Gallbladder and Extrahepatic Biliary System in Small Animals
Cholecystitis in Small Animals
Canine Gallbladder Mucocele
Other Disorders of the Gallbladder in Small Animals
Other Disorders of the Bile Ducts in Small Animals
Extrahepatic Bile Duct Obstruction in Small Animals
Cholelithiasis in Small Animals
Biliary Tree Rupture and Bile Peritonitis in Small Animals
Feline Cholangitis/Cholangiohepatitis Syndrome
Hepatobiliary Fluke Infection in Small Animals
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