Tetanus toxemia is caused by a specific toxin, or poison, that blocks the transmission of inhibitory nerve signals, resulting in severe contractions of muscles and exaggerated muscle responses to stimuli. The toxin is produced by Clostridium tetani bacteria in dead tissue. Almost all mammals are susceptible to this disease, although cats seem much more resistant than other domestic animals.
Clostridium tetani is found in soil and intestinal tracts. In most cases, it is introduced into the body through wounds, particularly deep puncture wounds. The bacteria remain in the dead tissue at the original site of infection and multiply. As bacterial cells die and disintegrate, the potent nerve toxin is released. The toxin causes convulsions of the voluntary muscles.
The incubation period varies from one to several weeks but usually averages 10 to 14 days. Localized stiffness, often involving the jaw muscles and muscles of the neck, the hind limbs, and the region of the infected wound, is seen first. General stiffness becomes pronounced approximately 1 day later, and then spasms and painful sensitivity from a normally painless touch become evident. Spasms are often triggered by sudden movement or noise. Because of their high resistance to tetanus toxin, cats often have a long incubation period and frequently develop tetanus that is localized to the area of the wound. However, generalized tetanus does develop, in which the ears are erect, the tail is stiff and extended, and the mouth is partially open with the lips drawn back.
Tetanus is diagnosed based on an animal's history of having a wound and the presence of signs. Laboratory tests may sometimes also be necessary. In the early stages of the disease, your veterinarian may recommend muscle relaxants, tranquilizers, or sedatives along with tetanus antitoxin. This treatment is supported by draining and cleaning the wounds and administering antibiotics.
Good nursing is critical during the early period of spasms. If your pet has tetanus and will be returning home with you rather than staying in a clinic, be sure to follow the nursing care instructions fully and carefully.