Anemia of chronic disease can be characterized as mild to moderate, nonregenerative, normochromic, and normocytic. It is the most common form of anemia seen in animals. The anemia can be secondary to chronic inflammation or infection, neoplasia, liver disease, hyper- or hypoadrenocorticism, or hypothyroidism. The anemia is mediated by cytokines produced by inflammatory cells, which lead to decreases in iron availability, RBC survival, and the marrow’s ability to regenerate. Treatment should be directed at the underlying disease and often results in resolution of the anemia.
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Also see Pet Health content regarding anemia of chronic disease in dogs Anemia of Chronic Disease Anemia occurs when there is a decrease in the number of red blood cells, which can be measured by red blood cell count or hemoglobin concentration. It can develop from loss, destruction, or... read more , anemia of chronic disease in cats Nonregenerative Anemias , and anemia of chronic disease in horses Nonregenerative Anemias .