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Transmissible Venereal Tumor in Dogs


Michelle Kutzler

, DVM, MBA, PhD, DACT, Oregon State University

Last full review/revision Jun 2018 | Content last modified Oct 2020

Transmissible venereal tumors are cancerous tumors of the genitalia in dogs. The tumor cells are passed from dog to dog during breeding. They form cauliflower-like masses that range in size from small (less than 5 millimeters wide) to large (more than 10 centimeters wide). The surface is often ulcerated and inflamed and bleeds easily. The tumors may be single or multiple. Although they are almost always located directly on the genitalia, they may be passed on to the adjacent skin or the mucous membranes of the mouth, nose, or eyes. Diagnosis is made by examining tumor cells under a microscope. Transmissible venereal tumors are usually progressive and are treated with a combination of surgical removal, chemotherapy, and radiation treatment. Of these, chemotherapy is generally considered the treatment of choice. The outlook for successful treatment is good, except in the rare cases in which the tumors have already spread within the body before treatment begins.

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Disorders of Calcium Metabolism
Calcium, in its ionic form, plays a key role in the function of many body systems. Precise control of calcium ion concentrations in extracellular fluids is regulated by several hormones. Which of the following is NOT involved in calcium homeostasis?
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