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Hypermagnesemia

By

Allison J. Stewart

, BVSC (Hons), MS, DACVIM-LA, DACVECC, The University of Queensland

Last full review/revision Sep 2013 | Content last modified Sep 2013

Hypermagnesemia (plasma Mg concentration >2 mg/dL [1.1 mmol/L]) is a rare condition reported only in monogastric animals. Horses show signs of sweating and muscle weakness within 4 hr of receiving excessive oral doses of magnesium sulfate administered as a cathartic for treatment of large-intestinal impactions. This is followed by recumbency, tachycardia (120 bpm), and tachypnea (60 breaths/min). Signs subside after treatment with slow IV infusion of calcium gluconate (23% solution). Hypermagnesemia has been reported in cats with renal failure that were receiving IV fluid therapy. As plasma Mg concentrations exceed 2.5 mmol/L, there may be ECG changes with prolongation of the PR interval; at 5 mmol/L, deep tendon reflexes disappear, followed by hypotension and respiratory depression. Cardiac arrest may occur with blood Mg levels >6.0–7.5 mmol/L.

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Equine Metabolic Syndrome
Equine metabolic syndrome is an abnormality in carbohydrate metabolism. It is often associated with obesity and increased fat deposition in the neck and tail head regions. The syndrome is common in some breeds but rare in others. Which of the following breeds does NOT show a predisposition for this syndrome?
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