Major Chemical Classes of Endocrine Hormones

Hormone Type

Means of Production

Site of Receptor Population

Structure in Different Species

Protein and polypeptide hormones

(eg, ACTH, insulin)

Gene transcription/translation

Cell surface

Variable (some identical, some not)

Steroid hormones

(eg, estrogen, cortisol)

Conversion from cholesterol

Intracellular

Identical

Modified amino acid hormones

(eg, thyroxine, catecholamines)

Modification of tyrosine

Intracellular (thyroxine) and cell surface (catecholamines)

Identical