MSD Manual

Please confirm that you are a health care professional

honeypot link

Feline Hypokalemic Polymyopathy

By

Joseph Harari

, MS, DVM, DACVS, Veterinary Surgical Specialists, Spokane, WA

Last full review/revision Nov 2020 | Content last modified Nov 2020

Feline hypokalemic polymyopathy is a generalized metabolic muscle weakness disorder in cats secondary to hypokalemia associated with excessive urinary depletion or inadequate dietary intake. Extracellular hypokalemia causes muscle cell membrane hyperpolarization and secondary excessive permeability to sodium. This leads to hypopolarization of the muscle cell and subsequent weakness.

Clinical signs include generalized weakness, ventroflexion of the neck, abnormal gait, anorexia, and muscle pain. The neurologic examination is normal. Serum chemistries reveal hypokalemia (<3.5 mEq/L) and increased creatinine and CK. The urine has a low specific gravity, and potassium excretion is increased. Treatment is by potassium supplementation, given PO (5–8 mEq/day) or IV in cats with profound hypokalemia. Prognosis is excellent with early diagnosis and treatment.

For More Information

Others also read
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID

Test your knowledge

Lameness
The lameness examination is an important method to identify musculoskeletal abnormalities. Which of the following abnormalities is NOT observed during a physical and lameness exam? 
Become a Pro at using our website 

Also of Interest

Become a Pro at using our website 
TOP