MSD Manual

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Professional Version

Spiroindoles

By

Jozef Vercruysse

, DVM, Ghent University;


Edwin Claerebout

, DVM, PhD, DEVPC, Laboratory of Parasitology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Belgium

Last full review/revision Sep 2014 | Content last modified Oct 2014

Derquantel has been approved as a combination anthelmintic product with abamectin. By adding abamectin to derquantel, the spectrum of parasite species against which this combination exhibits ≥95% efficacy is significantly increased. At the dose rate selected for the combination product, derquantel has excellent anthelmintic activity against the adult and L4 stages of Trichostrongylus spp and Nematodirus spp and the adult stage of Haemonchus spp, and has demonstrated variable efficacy against Teladorsagia circumcincta and the L4 stages of H contortus.

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