Changes in tracheal mucosa, Mycoplasma infection, photomicrographs

1) Normal tracheal mucosa with pseudostratified, simple columnar ciliated epithelium with goblet cells and two or three cell layers thick submucosa followed by muscularis mucosa. Mucosa and submucosa are measured at 49.65 mcm. 2) Moderate epithelial metaplasia and loss of cilia; the submucosa is moderately thickened by lymphocytic infiltration with germinal center formation. Mucosa and submucosa are measured at 238.1 mcm. 3) Severe epithelial metaplasia and loss of cilia; the submucosa is moderately thickened by lymphocytic infiltration with germinal center formation. Mucosa and submucosa are measured at 546.0 mcm. A) Scale bar = 60 mcm; 40X objective lens. B) Scale bar = 300 mcm; 10X objective lens.