Lead poisoning, blood smear, basophilic stippling, dog

Photomicrograph of a blood smear from a dog with lead poisoning. Hematological abnormalities indicative (but not confirmatory) of lead poisoning include basophilic stippling in an erythrocyte (note variably sized multiple basophilic inclusions in one centrally located erythrocyte) and metarubricytosis (note the presence of a nucleated erythrocyte (metarubricyte RBC). Three mature neutrophils are also present. Wright-Giemsa stain; original magnification 1000X, oil immersion.