<i >Mycoplasma</i> colonies, photomicrograph

Mycoplasma colonies, photomicrograph

Photomicrograph (subgross view) showing the classic Mycoplasma colonies (red arrows) with dark centers surrounded by the typical circular periphery ("fried egg" appearance) on modified Frey's agar. Notice the size variability is mostly in the periphery of the colony, whereas the centers remain relatively constant in size. Also notice that some colonies are merging (black arrows). Scale bar = 249 mcm; 4X objective lens.

Courtesy of Dr. Mohamed El-Gazzar.