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Spongiosis in bovine spongiform encephalopathy
spongiosis-in-bovine-spongiform-encephalopathy-badiola-sized
Spongiosis in bovine spongiform encephalopathy

    Micrograph showing dramatic vacuolization, also known as "spongiosis", in the CNS of a cow infected with bovine spongiform encephalopathy (hematoxylin-eosin staining).

Courtesy of Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Universidad de Zaragoza.