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Anticipated Laboratory Results for Different Causes of Hypercalcemia

Anticipated Laboratory Results for Different Causes of Hypercalcemia

Ionized Calcium

Total Calcium

PTH

PTHrP

Phosphorus

Calcidiol

Calcitriol

Granulomatous

↓N

↑N

↑N

N

↑N

Osteolytic

↑N

↑N

N

N

PHPT

↑N

N

↓N

N

↑N

Vitamin D toxicosis

N

N

Addison

↓N

N

↑N

N

↓N

Acute renal disease

↓N

N

↑N

N

↓N

Chronic renal disease

↓N

↑↓N

N

↑N

↓N

↓N

Nutritional

↓N

↓N

N

↑N

↓N

↓N

Tertiary HPT

N

↓N

↓N

Neoplasia

↓N

↑N

↓N

N

↑↓N

Idiopathic

↓N

N

↑N

↓N

↑↓N