Antimicrobial Treatment for R equi in Foals

Drug

Dose, Route, Frequency

Usage Instructions

Erythromycin (as estolate or base)

25 mg/kg, PO, every 6–8 h

In combination with rifampin

Erythromycin (as lactobionate)

5 mg/kg, IV, every 6 h

In combination with rifampin

Clarithromycin

7.5 mg/kg, PO, every 12 h

In combination with rifampin

Azithromycin

10 mg/kg, PO, every 24 h for 5 days, then every 48 h

5 mg/kg, IV, every 24 h × 5 days, then every 48 h

In combination with rifampin

Rifampin

5 mg/kg, PO, every 12 h

In combination with a macrolide