Assessment of Regeneration in Anemia

Parameter

Regenerative Anemia

Nonregenerative Anemia

Absolute reticulocyte count

In dogs: > 60,000 reticulocytes/mcL

In cats: > 50,000 aggregate reticulocytes/mcL*

In dogs: < 60,000 reticulocytes/mcL

In cats: < 50,000 aggregate reticulocytes/mcL*

Corrected reticulocyte percentage

> 1%

< 1%

Mean corpuscular volume

Macrocytosis

Microcytosis to normocytosis

Mean corpuscular hemoglobin concentration

Hypochromia

Normochromia

Other characteristics

Polychromasia, nucleated RBCs

Lack of response in 3–5 days

*For cats (which have both aggregate and puntate reticulocytes), only aggregate reticulocytes are included in a reticulocyte count.