Adrenal

Adrenal

(primary)

Primary hypoadrenocorticism

Addison disease Addison Disease Addison disease (hypoadrenocorticism) results from the lack of glucocorticoids, mineralocorticoids, or both. Isolated aldosterone insufficiency appears to be very rare, whereas isolated glucocorticoid... read more , loss of cortisol and aldosterone

Occasional in dogs and cats

Functional adrenal tumor (hyperadrenocorticism [ Cushing syndrome Cushing Syndrome (Hyperadrenocorticism) Cushing syndrome refers to any cause of elevated cortisol concentrations. Pituitary-dependent hyperadrenocorticism (PDH; Cushing disease) is the most common form of hyperadrenocorticism and... read more ])

Occasional in dogs; common in ferrets but involves secretion of excess sex steroids

Thyroid

Thyroid

(primary)

Primary hypothyroidism Hypothyroidism in Animals Hypothyroidism is thyroid hormone deficiency. It is diagnosed by clinical features such as lethargy, weight gain, obesity, haircoat changes, and low serum thyroid hormone concentrations. Management... read more

Common in dogs

Hyperthyroidism Hyperthyroidism in Animals Hyperthyroidism is characterized by hypermetabolism and high circulating thyroid hormone concentrations. Clinical features include weight loss despite a good appetite. Treatment depends on the... read more

Very common in cats

Parathyroid

Parathyroid

(primary)

Primary hypoparathyroidism Primary Hyperparathyroidism Hypercalcemia is diagnosed when calcium is elevated outside of normal reference ranges. This usually indicates an underlying disease process causing the dysregulation of calcium homeostasis... read more

Low PTH

Rare in dogs or cats

Primary hyperparathyroidism Renal Secondary Hyperparathyroidism In primary hyperparathyroidism, there is excess production of parathyroid hormone (PTH) by an autonomous functional lesion in one or several of the parathyroid glands. The normal regulatory... read more

High PTH

Occasional in dogs and cats

Pancreas

Pancreas

(primary)

Diabetes mellitus Diabetes Mellitus in Dogs and Cats Diabetes mellitus is a common endocrine disease in dogs and cats, occurring in about 1 of every 300 patients. Clinical signs reflect hyperglycemia with resultant glycosuria. Diagnosis is made... read more type I

Low insulin

Common in dogs

Insulinoma Functional Islet Cell Tumors in Small Animals Islet cell tumors are the most common cause of hypoglycemia in older dogs. Clinical signs vary but often consist of weakness, ataxia, collapse and seizures. Diagnosis is by documenting hypoglycemia... read more

High insulin

Occasional in dogs; common in ferrets