Dosages of Macrolides
Dosages of Macrolides
Macrolide | Species | Dosage, Route, and Frequency | Notes |
|---|---|---|---|
Erythromycin | Beef cattle | No approved veterinary erythromycin products are available in the US | |
Cats | 15 mg/kg, PO, q 8 h | ELDU | |
Foals | 20–25 mg/kg, PO, q 6–8 h using erythromycin base or estolate products | Do not use in adult horses | |
Tylosin | Cattle | 17.6 mg/kg, IM, q 24 h for up to 5 days | |
Pigs | 8.8 mg/kg, IM, q 12 h for up to 3 days | ||
Dogs, cats | 6–20 mg/kg, PO, q 8–24 h | ELDU | |
Honeybees | 200 mg/hive, q 7 d for 3 wk | ||
Tilmicosin | Beef cattle Dairy cattle < 20 mo | 10–20 mg/kg, SC, once | Accidental self-injection can be fatal to humans |
Sheep | 10 mg/kg, SC, once | ||
Tulathromycin | Cattle | 2.5 mg/kg, SC, once | |
Swine | 2.5 mg/kg, IM, once | ||
Gamithromycin | Beef cattle Dairy cattle < 20 mo | 6 mg/kg, SC, once | |
Tildipirosin | Beef cattle Dairy cattle < 20 mo | 4 mg/kg, SC, once | |
Azithromycin | Dogs | 5–12 mg/kg, PO, q 24 h | Off-label |
Cats | 5–15 mg/kg, PO, q 24 h | Off-label | |
Foals | 10 mg/kg, PO, q 24 h usually in combination with rifampin at 5 mg/kg, PO, q 12 h | Off-label; Do not use in adult horses | |
Clarithromycin | Foals | 5–7.5 mg/kg, PO, q 12 h | Off-label; Do not use in adult horses |
Dogs | 5-10 mg/kg, PO, q 12 h | ||
Cats | 7.5 mg/kg, PO, q 12 h | ||
Clindamycin | Dogs | 5-10 mg/kg, PO, q 12 h | |
Cats | 7.5 mg/kg, PO, q 12 h | ||
ELDU, extralabel drug use |