Tetracycline

Cats, dogs

4.4–11 mg/kg, IM or IV, q 8–12 h

22 mg/kg, PO, q 8 h for 14–28 days

ELDU; there are no injectable tetracycline products available in the US

Oxytetracycline

Cats, dogs

10 mg/kg, IV, q 12 h

Dogs, cats

20 mg/kg, PO, q 8 h

Cattle, excluding veal

6.6–11 mg/kg, SC, IM, or IV, q 24 h for up to 4 days

20 mg/kg, SC or IM, once

Honeybees

200 mg/hive, q 7 d for 3 treatments

Swine

6.6 mg/kg, IV, once

6.6–11 mg/kg, IM, q 24 h

20 mg/kg, IM, once

Horses

6.6 mg/kg, IV, q 12–24 h

ELDU

Doxycycline

Dogs, cats

5–10 mg/kg, PO, q 24 h

ELDU;

administration of solid dosage forms to cats should be followed by food or at least 6 mL of liquid to prevent esophageal erosions

Dogs

10 mg/kg, PO, q 12 h for 30 days

ELDU; before heartworm adulticide treatment

Horses

10 mg/kg, PO, q 12 h

ELDU; never administer IV

Minocycline

Dogs, cats

5–10 mg/kg, PO, q 12 h

ELDU

Horses

4 mg/kg, PO, q 12 h

ELDU