Drugs Commonly Used for Trypanosomiasis in Domestic Animals
Drug | Animal | Trypanosoma | Main Action | Administration Route(s) | Dosage (mg/kg) |
|---|---|---|---|---|---|
Diminazene aceturate | Cattle | vivax, congolense, brucei | Curative | IM, SC | 3.5–7 |
Homidium bromide | Cattle | vivax, congolense, brucei | Curative, some prophylactic activity | IM (deep), IV (sheep, goats, pigs) | 1 |
Homidium bromide | Equids | vivax | Curative, some prophylactic activity | IV | 1 |
Homidium chloride | Equids | vivax | Curative, some prophylactic activity | IV | 1 |
Isometamidium chloride | Cattle | vivax, congolense | Curative and prophylactic | IM (deep) | 0.25–1 |
Quinapyramine sulfate | Horses, camels, pigs, dogs | vivax, congolense, brucei, evansi, equiperdum, simiae | Curative | SC | 3–5 |
Quinapyramine dimethylsulfate | Horses, camels, pigs, dogs | vivax, congolense, brucei, evansi, equiperdum, simiae | Prophylactic | SC | 3–5 |
Suramin | Horses, camels, dogs | brucei, evansi | Curative, some prophylactic activity | IV | 10 |
Melarsomine dichlorhydrate | Camels | evansi | Curative | SC, IM | 0.25–0.5 |