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Drugs for Intestinal Helminths of Cats Approved in the US and UK

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Learn about SectionName symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!

Drug or Drug Combination	Dosage (mg/kg), Frequency	Route of Administration	Helminths Active Against^a
*Approved in both US and UK*
Emodepside + praziquantel	3/12, once	Topical	Toxocara cati, Ancylostoma tubaeforme, Dipylidium caninum, Taenia taeniaeformis
Moxidectin + imidacloprid	1/10, monthly	Topical	T cati, A tubaeforme
Selamectin	6, monthly	Topical	T cati, A tubaeforme
*Approved only in US*
Epsiprantel	2.75, once	PO	D caninum, T taeniaeformis
Ivermectin	0.024, monthly	PO	A tubaeforme, Ancylostoma braziliense
Milbemycin oxime	2, monthly	PO	T cati, A tubaeforme
Piperazine (various salts)	48–88, once; repeat after 10 days^b	PO	T cati, Toxascaris leonina
Praziquantel	4.6–10, once	PO	D caninum, T taeniaeformis
Praziquantel	5–10, once	SC, IM	D caninum, T taeniaeformis
Praziquantel + pyrantel pamoate	5/20, once	PO	T cati, A tubaeforme, D caninum, T taeniaeformis
Eprinomectin + praziquantel	0.51/10.0, monthly	Topical	T cati, A tubaeforme, A braziliense, D caninum, Echinococcus multilocularis
Moxidectin + fluralaner	2/40, monthly	Topical	T cati, A tubaeforme
Selamectin + sarolaner	6/1, monthly	Topical	T cati, A tubaeforme
*Approved only in UK*
Emodepside + praziquantel	3/12, once	Topical	T leonina, E multilocularis, Aelurostrongylus abstrusus^c
Fenbendazole	100 once, or 50 daily for 3 days	PO	T cati, T leonina, Ancylostoma spp, Uncinaria spp, Taenia spp, A abstrusus
Praziquantel	5, once	PO	D caninum, T taeniaeformis, E multilocularis^c
Praziquantel	8–10, monthly	Topical	D caninum, Taenia spp, E multilocularis
Milbemycin oxime + praziquantel	2–8/5–10, monthly	PO	T cati, A tubaeforme, D caninum, Taenia spp, E multilocularis
Moxidectin + imidacloprid	1/10, monthly	Topical	A abstrusus,^cEucoleus aerophilus, Thelazia callipaeda^c
Praziquantel + pyrantel embonate	5/57.5, once	PO	T cati, T leonina,^cA tubaeforme,^cA braziliense,^cD caninum, T taeniaeformis, E multilocularis, Mesocestoides spp,^cJoyeuxiella pasqualei^c
Eprinomectin + praziquantel + fipronil + methoprene	0.5/10/10/12, monthly	Topical	T cati, T leonina, A tubaeforme, A braziliense, Ancylostoma ceylanicum, D caninum, T taeniaeformis, E multilocularis, J pasqualei, Joyeuxiella fuhrmanni, A abstrusus, Capillaria plica, Troglostrongylus brevior
^a Many of these drugs are also approved for use against other types of parasites (eg, fleas, heartworm) not listed here.
^b Repeat after 10–14 days for most products.
^c Only some products.