Table: Drugs for Intestinal Helminths of Cats Approved in the US and UK

Drugs for Intestinal Helminths of Cats Approved in the US and UK

Drug or Drug Combination	Dosage (mg/kg)	Route of Administration	Helminths Active Against^a
*Approved only in US*
Epsiprantel	2.75, once	PO	Dipylidium caninum, Taenia taeniaeformis
Ivermectin	0.024, monthly	PO	Ancylostoma tubaeforme, Ancylostoma braziliense
Milbemycin oxime	2, monthly	PO	Toxocara cati, A tubaeforme
Piperazine (various salts)	48–88, once^{b, d}	PO	T cati, Toxascaris leonina
Praziquantel	4.6–10, once	PO	D caninum, T taeniaeformis
Praziquantel	5–10, once	SC, IM	D caninum, T taeniaeformis
Praziquantel + pyrantel pamoate	5/20, once	PO	T cati, A tubaeforme, D caninum, T taeniaeformis
Eprinomectin + praziquantel	0.51/10.0, monthly	Topical	T cati, A tubaeforme, A braziliense, D caninum, Echinococcus multilocularis
Moxidectin + fluralaner	2/40, monthly	Topical	T cati, A tubaeforme
Selamectin + sarolaner	6/1, monthly	Topical	T cati, A tubaeforme

*Approved only in UK*
Fenbendazole	100 once, or 50 daily for 3 days	PO	T cati, T leonina, Ancylostoma spp, Uncinaria spp, Taenia spp, Aelurostrongylus abstrusus
Praziquantel	5, once	PO	D caninum, T taeniaeformis, E multilocularis^c
Praziquantel	8	Topical	D caninum, Taenia spp, E multilocularis
Milbemycin oxime + praziquantel	2/5 monthly	PO	T cati, A tubaeforme, D caninum, Taenia spp, E multilocularis
Praziquantel + pyrantel embonate	5/57.5, once	PO	T cati, T leonina_c, A tubaeforme_c, A braziliense_c, D caninum, T taeniaeformis, E multilocularis, Mesocestoides spp_c, Joyeuxiella pasqualei_c
Eprinomectin + praziquantel + fipronil + methoprene	0.5/10/10/12, monthly	Topical	T cati, T leonina, A tubaeforme, A braziliense, Ancylostoma ceylanicum, D caninum, T taeniaeformis, E multilocularis, J pasqualei, Joyeuxiella fuhrmanni, A abstrusus, Capillaria plica, Troglostrongylus brevior

*Approved in both US and UK*
Emodepside + praziquantel	3/12, once	Topical	T cati, T leonina_e, A tubaeforme, D caninum, T taeniaeformis, E multilocularis^e,A abstrusus_ce
Moxidectin + imidacloprid	1/10, monthly	Topical	T cati, A tubaeforme, A abstrusus_ce, Eucoleus aerophilus_e, Thelazia callipaeda_c_e
Selamectin	6, monthly	Topical	T cati, A tubaeforme
^a Many of these drugs are also approved for use against other types of parasites (eg, fleas, heartworm) not listed here.
^b Repeat in 10–14 days for most products
^c Only some products
^d Only in the US
_e Only in the UK

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Drugs for Intestinal Helminths of Cats Approved in the US and UK