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Learn about SectionName symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!

Active Ingredient(s)	Dose (range)	Application	Protection onset	Duration of Protection
Deltamethrin	40 mg/g	Collar	7 days	1 yr
Flumethrin, imidacloprid	56 mg/g	Collar	Unknown	8 mo
Permethrin	47.6 mg/kg	Spot-on	24–48 h	2 wk
Permethrin	Not applicable	Spray	Instant	2–3 d
Permethrin, dinotefuran, pyriproxyfen	46.6–158.8 mg/kg	Spot-on	24–48 h	4 wk
Permethrin, fipronil	50.5–160 mg/kg	Spot-on	24–48 h	4 wk
Permethrin, imidacloprid	50–125 mg/kg	Spot-on	24–48 h	3–4 wk
Permethrin, indoxacarb	48–96 mg/kg	Spot-on	24–48 h	3–4 wk
Adapted from Miró G, Petersen C, Cardoso L, et al. Novel areas for prevention and control of canine leishmaniosis. Trends Parasitol. 2017;33(9)718-730. doi:10.1016/j.pt.2017.05.005