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Information that is clear and easy to understand on thousands of medical disorders and symptoms

Learn about SectionName symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!

Location	Disease	Mechanism
Luminal	Exocrine pancreatic insufficiency	Lack of pancreatic enzymes (maldigestion)
Luminal	Small-intestinal dysbiosis Antibiotic-responsive diarrhea Secondary small-intestinal bacterial overgrowth	Bacterial activity: bile salt deconjugation, fatty acid hydroxylation, competition for cobalamin and nutrients
Mucosal	Infectious enteropathies Protozoal Fungal Hookworms Chronic inflammatory enteropathy Inflammatory bowel disease Dietary sensitivity Neoplastic infiltration	Mucosal damage: inflammation, brush border defects, disturbed enterocyte function, reduction of surface area
Mucosal	Villous atrophy	Reduction in surface area, immature enterocytes due to increased cell turnover with reduced brush border enzyme expression
Mucosal	Inherited and acquired brush border enzyme deficiencies	Lactase deficiency, diffuse small-intestinal disease
Postmucosal	Lymphangiectasia	Lymphatic obstruction impairs delivery of chylomicrons
Postmucosal	Vasculitis, portal hypertension	Impaired delivery