Pharmacokinetics of Selected Fluoroquinolones
Drug | Species | Route | Elimination Half-life (h) | Volume of Distribution (L/kg) | Clearance (mL/min/kg) |
|---|---|---|---|---|---|
Enrofloxacin | Cats | IV | 7 | 4 | 9.5 |
Dogs | IV | 2.52 | 2.35 | 11.9 | |
Horses | IV | 6.15 | 2.32 | 6.34 | |
Cattle | IV | 2.8 | 2.98 | 8.1 | |
Swine | IV | 16.1 | 3.59 | 3.3 | |
Marbofloxacin | Dogs | IV | 8.08 | 2.32 | 3.83 |
Cats | IV | 7.97 | 4.84 | 8 | |
Horses | IV | 7.42 | 1.6 | 4.62 | |
Orbifloxacin | Horses | IV | 5.08 | 1.58 | 4.6 |
Dogs | IV | 4.23 | 1.95 | 5.16 |