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Pharmacokinetics of Selected Fluoroquinolones

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Learn about SectionName symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!

Drug	Species	Route	Elimination Half-life (h)	Volume of Distribution (L/kg)	Clearance (mL/min/kg)
Enrofloxacin	Cats	IV	7	4	9.5
	Dogs	IV	2.52	2.35	11.9
	Horses	IV	6.15	2.32	6.34
	Cattle	IV	2.8	2.98	8.1
	Swine	IV	16.1	3.59	3.3
Marbofloxacin	Dogs	IV	8.08	2.32	3.83
	Cats	IV	7.97	4.84	8
	Horses	IV	7.42	1.6	4.62
Orbifloxacin	Horses	IV	5.08	1.58	4.6
	Dogs	IV	4.23	1.95	5.16