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Poisonous Mushrooms: Onset of Action and Organs Targeted

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Learn about SectionName symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!

Mushrooms	Toxin	Onset Time	Organ/System Affected
*Latent Period >6 hr After Ingestion; Life-threatening*
Amanita phalloides,A ocreata, A bisporigera	Cyclopeptides, alpha, beta, and gamma amanitins	6–24 hr, rarely >24 hr	Primarily liver, kidney secondarily
Conocybe filaris	Alpha and beta amanitins	6–24 hr, rarely >24 hr	Primarily liver
Cortinarius orellanosus, C rubellus	Orellanine	3–14 days	Primarily renal
Galerina marginata	Alpha and beta amanitins	6–24 hr, rarely >24 hr	Primarily liver
Gyromitra esculenta	Monomethylhydrazine	6–24 hr	CNS
Lepiota spp	Alpha and beta amanitins	6–24 hr, rarely >24 hr	Primarily liver
*Latent Period ≤3 hr After Ingestion; Not Life-threatening*
Amanita muscaria, A pantherina	Isoxazoles: ibotenic acid and muscimol	30 min–2 hr; recovery 4–24 hr	CNS
Chlorophyllum molybdites	Unknown	15 min–3 hr; recovery 1–2 days	Gastrointestinal
Clitocybe spp, Inocybe spp	Muscarine	15 min–2 hr; recovery 6–24 hr	Autonomic nervous system
Paxillus involutus	Unknown	1–3 hr; recovery 2–4 days	Gastrointestinal, immune system (rare)
Psilocybe spp, Conocybe spp, Gymnopilus spp, Panaeolus spp	Psilocybin and psilocin	30–60 min; recovery 6–12 hr	CNS
Russula emetica	Unknown	30 min–3 hr; recovery 1–2 days	Gastrointestinal