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Primary Regulators of Calcium Homeostasis

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Generic Drug Names A - Z

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Information that is clear and easy to understand on thousands of medical disorders and symptoms

Learn about SectionName symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!

Hormone	Synthesis Location	Effects on Kidney	Effects on Bone	Effects on Intestine
PTH	Chief cells of parathyroid gland	Calcium reabsorption, phosphorus excretion, increases calcitriol formation	Calcium and phosphorus reabsorption	Increases calcitriol formation, which then increases calcium and phosphorus absorption
Calcitriol	Kidney	Calcium and phosphorus reabsorption	Normal development	Increases calcium and phosphorus absorption
Calcitonin	C cells of thyroid gland	Phosphorus excretion	Inhibits osteoclasts	None
PTHrP	Fetal parathyroid glands, tumors, other tissues	Calcium reabsorption, phosphorus excretion	Growth plate development, calcium and phosphorus reabsorption	None
PTH, parathyroid hormone; PTHrP, parathyroid hormone-related protein