Synthetic Colloid Fluid Types
Colloid | In Solution With | Average Molecular Weight, kDa | Average (and Range of) Molecular Weight, kDa | C2:C6 Ratio | Colloid Oncotic Pressure, mm Hg | Suggested Upper Limit, dose/kg/d | Concentration, % |
|---|---|---|---|---|---|---|---|
Dextran 70 | 0.9% NaCl | 70 | 10–80 | NA | 59 | 20 mL | 6 |
Hextend (670/0.7) x | Lactated electrolyte solution | 670 | 20–2,500 | 5:1 | 25–30 | 20 mL | 6 |
VetStarch/Voluven (130/0.4) | 0.9% NaCl | 130 | 110–150 | 9:1 | 36 | 50 mL | 6 |
HESPAN (600/0.4) | 0.9% NaCl | 600 | 450–800 | 5:1 | 25–30 | 20 mL | 6 |
Stroma-free hemoglobin | Modified lactated Ringer's solution | 65–130 | Up to 500 | NA | 20 | See text | 13 |
Abbreviations: kDa, kilodaltons; NA, not applicable. C2:C6 ratio describes the position of the hydroxyethyl groups on the glucose units; a higher ratio indicates a greater resistance to degradation by amylase, indicating a longer plasma half-life. | |||||||