Synthetic Steroidal and Nonsteroidal Estrogen Hormone Growth Promotants in Cattle and Sheepa

Synthetic Steroidal and Nonsteroidal Estrogen Hormone Growth Promotants in Cattle and Sheepa

Hormoneb

Doseb.c

Duration of Effect (days)

Growth Response

Potential Adverse Effects

TBA

200 mg (heifers)

60–90

5%–12%

TBA + EB

200 mg TBA + 28 mg EB (steers and heifers)

150–200

10%–20%

Transient increase in sexual behavior

Udder development

Vaginal and rectal prolapse

Ventral edema

100 mg TBA + 14 mg EB (steers and heifers)

100–140

10%–20%

Transient increase in sexual behavior

Udder development

Vaginal and rectal prolapse

Ventral edema

150 mg TBA + 21 mg EB (coated implant, steers and heifers grazing pasture)

180–200

10%–20%

200 mg TBA + 28 mg EB (coated implant, steers and heifers)

200

TBA + E

200 mg TBA + 20 mg E (steers and heifers)

80–120

200 mg TBA + 20 mg E (coated implant, heifers)

Initial and delayed release implant that provides hormonal payout for up to 200 days after implantation

200 mg TBA + 20 mg E (coated implant, steers)

Delayed release implant that does not begin hormonal payout until ~70 days after implantation

200 mg TBA + 40 mg E (coated implant, steers)

Initial and delayed release implant that provides hormonal payout for up to 200 days after implantation

120 mg TBA + 24 mg E (steers)

100–140

140 mg TBA + 14 mg E (heifers)

100–140

80 mg TBA + 16 mg E (steers)

100–140

80 mg TBA + 8 mg E (heifers)

100–140

40 mg TBA + 8 mg E (steers and heifers grazing pasture)

100–140

Zeranol

36 mg

70–100

10%–15%

)12 mg

90–120

10%–15%

Melengestrol acetate

0.25–0.50 mg/day (heifers)

For the intended duration

3%–10%

Increased mammary development after long-term administration

a Individual product labeling should be consulted for specific purposes and dosages in food-producing animals.

b E, estradiol 17-beta; EB, estradiol benzoate; TBA, trenbolone acetate.

c All administered as pellet implants except melengestrol acetate, which is administered in feed.

a Individual product labeling should be consulted for specific purposes and dosages in food-producing animals.

b E, estradiol 17-beta; EB, estradiol benzoate; TBA, trenbolone acetate.

c All administered as pellet implants except melengestrol acetate, which is administered in feed.