Toxic Causes of Anemia

Pathogenic Mechanism

Drugs

Plants, Foods

Toxins, Chemicals

Heavy Metals

Oxidation

Acetaminophen, benzocaine, dapsone, nitrofurans, primaquine, propofol, quinacrine

Fava beans, oak, onions, propylene glycol, red maple

Crude oil, naphthalene

Copper, zinc

Blood loss

Aspirin, naproxen, NSAIDs (GI ulceration)

Bracken fern, sweet clover

Dicumarol

Immune-mediated hemolysis

Cephalosporins, levamisole, penicillin, propylthiouracil, sulfonamides

Pirimicarb

Hemolysis

Fenbendazole, heparin

Indole

Lead, selenium

Decreased marrow production

Amphotericin, azidothymidine, cephalosporins, chloramphenicol, estrogen, fenbendazole, griseofulvin, meclofenamic acid, phenobarbital, phenothiazine, phenylbutazone, propylthiouracil, quinidine, recombinant human erythropoietin, sulfonamides, thiacetarsamide

Bracken fern

Benzene, trichloroethylene

Lead