Table: Inherited Cataracts in Domestic Animals

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Inherited Cataracts in Domestic Animals

Breed	Age of Onset	Initial Localization	Mode of Inheritance
*Dogs*
Afghan Hound	6–12 mo	Equatorial/posterior cortex	Autosomal recessive
American Cocker Spaniel	1–6 yr	Posterior/anterior cortex	Autosomal recessive polygenetic
Australian Shepherd	2–4 yr	Posterior cortex	Autosomal dominant^a
Bichon Frise	2–6 yr	Posterior/anterior cortex	Autosomal recessive
Boston Terrier	Congenital or juvenile Late onset	Posterior sutures/nuclear Equatorial/anterior cortex	Autosomal recessive^a Autosomal recessive
Chesapeake Bay Retriever	≥1 yr	Nuclear/cortex	Incomplete dominant
Entelbucher Mountain Dog	1–2 yr	Posterior cortex	Autosomal recessive
German Shepherd	≥8 wk	Posterior sutures/ cortex	Incomplete dominant
Golden Retriever	≥6 mo	Posterior subcapsular (triangular)	Incomplete dominant
Labrador Retriever	≥6 mo	Posterior subcapsular (triangular)	Incomplete dominant
Havanese	2–6 yr	Posterior/anterior cortex	Possible autosomal recessive
Miniature Schnauzer	Congenital ≥6 mo	Nuclear/posterior cortex Posterior cortex	Autosomal recessive Autosomal recessive
Norwegian Buhund	≥1 yr	Nuclear/cortex	Autosomal dominant
Old English Sheepdog	Congenital	Nuclear/cortex	Autosomal recessive
Rottweiler	≥10 mo	Posterior polar/complete	Unknown
Siberian Husky	≥6 mo	Posterior subcapsular/ posterior sutures	Autosomal recessive
Staffordshire Bull Terrier	≥6 mo	Posterior sutures/ cortex	Autosomal recessive^a
Standard Poodle	≥1 yr	Equatorial cortex	Autosomal recessive
Welsh Springer Spaniel	Congenital	Nuclear/posterior cortex	Autosomal recessive
West Highland White Terrier	Congenital	Posterior sutures	Autosomal recessive
*Horses*
Belgian	Congenital	Nuclear/cortex	Autosomal dominant
Morgan	Congenital	Nuclear	Autosomal dominant
*Cattle*
Holstein-Friesian	Congenital	Nuclear/cortex	Autosomal recessive
Jersey	Congenital	Nuclear	Autosomal recessive
*Sheep*
New Zealand Romney	Congenital	Anterior/posterior cortex	Autosomal dominant
^a Associated with mutations in HSF4 gene.

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Inherited Cataracts in Domestic Animals