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4-Ipomeanol Toxicosis (Moldy Sweet Potato) and Perilla Ketone Toxicosis (Purple Mint Toxicosis) in Cattle

By

John Campbell

, DVM, DVSc, Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan

Reviewed/Revised Dec 2022 | Modified Jun 2023

Moldy sweet potato toxicity is due to the ingestion of a furanoterpenoid toxin produced by sweet potatoes (Ipomoea batatas) in response to infestation with the fungus F solani; the end result is production of the pneumotoxin 4-ipomeanol. Perilla ketone toxicity is due to ingestion of the leaves and seeds of the plant P frutescens (purple mint), which contains a pneumotoxin and is found in the southeastern US. The pathogeneses of both these conditions are similar to that of ABPEE, as is approach to treatment.

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