MSD Manual

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Professional Version

Overview of Hormonal Control of Estrus


Juan E. Romano

, DVM, MS, PhD, DACT, Texas A&M University

Last full review/revision Apr 2021 | Content last modified Jul 2021

Hormones are commonly used to manipulate the estrous cycle. The major indications for hormonal control of estrus are to induce luteolysis, induce ovulation of a mature follicle, suppress estrus, induce cyclicity in anestrous animals, and superovulate cyclic animals. Effective treatments for these manipulations of the estrous cycle vary between species. Additionally, a number of treatments currently lack regulatory approval; prescribing veterinarians should follow label instructions and adhere to relevant laws and regulations.

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