Copper toxicosis, cholestasis, sheep, photomicrograph
Photomicrograph of liver tissue from a 2-year-old sheep with copper toxicosis. Note the severe vacuolar changes affecting hepatocytes (black arrows), as well as bile plugs from severe cholestasis (yellow arrows). Rare, light-green copper pigment is also evident (black arrowhead). Magnification 400X.
Courtesy of Dr. Trevor Arunsiripate.
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