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Carcinoides em animais

PorRobert J. Kemppainen, DVM, PhD, Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University
Revisado/Corrigido jul. 2023 | Modificado set. 2024
v82359977_pt

Carcinoids are a heterologous group of neuroendocrine tumors that occur in various regions of the GI tract, liver, lung, and occasionally heart. In dogs and cats, carcinoids have been reported to occur in the stomach.

Etiologia e patogênese dos carcinoides em animais

Carcinoid tumors arise from neuroectodermal cells.

In humans (but not yet documented in companion animals), carcinoid tumors serve as a source of serotonin or histamine. Excessive release of these transmitters can cause a syndrome of flushing, hypotension, wheezing, and diarrhea in humans.

In dogs and cats, carcinoid tumors may cause obstruction in the GI tract or metastasize to lymph nodes and other tissues.

Epidemiologia dos carcinoides em animais

Carcinoid tumors are rare in dogs and cats.

Características clínicas dos carcinoides em animais

Clinical signs of carcinoid tumors vary with the location of the tumor. The most common clinical signs include chronic vomiting, anorexia, diarrhea, and weight loss.

Diagnóstico dos carcinoides em animais

Carcinoids can be presumptively diagnosed based on signalment, history, clinical signs, physical examination findings, and results of diagnostic imaging. Definitive diagnosis of carcinoid tumors is determined histologically after biopsy or resection.

Tratamento e prognóstico dos carcinoides em animais

Surgical removal is the treatment of choice for carcinoid tumors.

In general, prognosis for carcinoid tumors is guarded. Metastasis is common at the time of diagnosis.

Pontos-chave

  • Carcinoids occur in various regions of the GI tract, liver, lung, and occasionally heart.

  • Surgical removal is the treatment of choice.