MSD Manual

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Hepatocyte, microvillar margin
Hepatocyte, microvillar margin

    Simple diagrammatic representation of hepatocyte microvillar membrane interfacing with the space of Disse where they increase surface contact for exchange purposes (nutrients, toxins). Canaliculi, the first conduit of bile collection are specialized regions of hepatocyte membranes. Integrity is maintained by tight junctions whereas gap junctions facilitate intercellular exchange and passage of cells.

Adapted from Qayed E, Srinivasan S, Shahnavaz N, eds. Sleisinger and Fordtran's Gastrointestinal and Liver Disease Review and Assessment. 10th ed. Elsevier, 2016.